Bis-aryl triazoles as selective inhibitors of 11beta-hydroxysteroid dehydrogenase type 1

MeSH terms

• 11-beta-Hydroxysteroid Dehydrogenase Type 1 / antagonists & inhibitors*
• Animals
• Binding Sites
• Disease Models, Animal
• Enzyme Inhibitors* / chemical synthesis
• Enzyme Inhibitors* / pharmacokinetics
• Enzyme Inhibitors* / therapeutic use
• Hydrocarbons, Aromatic* / chemical synthesis
• Hydrocarbons, Aromatic* / pharmacology
• Hydrocarbons, Aromatic* / therapeutic use
• Hypoglycemic Agents* / chemical synthesis
• Hypoglycemic Agents* / pharmacokinetics
• Hypoglycemic Agents* / therapeutic use
• Inhibitory Concentration 50
• Metabolic Syndrome / drug therapy*
• Mice
• Models, Chemical
• Structure-Activity Relationship
• Triazoles* / chemical synthesis
• Triazoles* / pharmacology
• Triazoles* / therapeutic use